Article
[The renin-angiotensin system as the basic principle for hypertension and coronary heart diseases--role of genetic factors].
Zeitschrift fur Kardiologie - 1 Apr 2000
Paul M
Abstract excerpt
Since the discovery of renin by Tigerstedt and Bergmann, the renin angiotensin system (RAS) has been recognized as an important modulator of blood pressure and volume homeostasis. Based on these functions a pathophysiological role of the RAS in the pathogenesis of hypertension and other cardiovascular disorders has been postulated. The therapeutic benefit of RAS inhibition by angiotensin converting enzyme (ACE)...
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