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Article

HRAS mutations are frequent in inverted urothelial neoplasms.

Human pathology - 1 Sept 2014

McDaniel Andrew S, Zhai Yali, Cho Kathleen R, Dhanasekaran Saravana M, Montgomery Jeffrey S, Palapattu Ganesh, Siddiqui Javed, Morgan Todd, Alva Ajjai, Weizer Alon, Lee Cheryl T, Chinnaiyan Arul M, Quist Michael J, Grasso Catherine S, Tomlins Scott A, Mehra Rohit

Abstract excerpt

Inverted urothelial papilloma (IUP) is an uncommon neoplasm of the urinary bladder with distinct morphologic features. Studies regarding the role of human papillomavirus (HPV) in the etiology of IUP have provided conflicting evidence of HPV infection. In addition, little is known regarding the molecular alterations present in IUP or other urothelial neoplasms, which might demonstrate inverted growth pattern like...

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Topics

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Share to Amino Acid Substitution
Share to Carcinoma, Transitional Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to In Situ Hybridization

Share to Papillomaviridae

Share to Papillomavirus Infections

Share to Proto-Oncogene Proteins p21(ras)

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25097040
DOI: 10.1016/j.humpath.2014.06.003
PMCID: PMC4241848

Genes

HRAS
BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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