Article
Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation.
American journal of human genetics - 1 Apr 2009
Alders Marielle, Koopmann Tamara T, Christiaans Imke, Postema Pieter G, Beekman Leander, Tanck Michael W T, Zeppenfeld Katja, Loh Peter, Koch Karel T, Demolombe Sophie, Mannens Marcel M A M, Bezzina Connie R, Wilde Arthur A M
Abstract excerpt
Idiopathic Ventricular Fibrillation (IVF) is defined as spontaneous VF without any known structural or electrical heart disease. A family history is present in up to 20% of probands with the disorder, suggesting that at least a subset of IVF is hereditary. A genome-wide haplotype-sharing analysis...
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