Article
Genome-wide mapping of the coactivator Ada2p yields insight into the functional roles of SAGA/ADA complex in Candida albicans.
Molecular biology of the cell - 1 May 2009
Sellam Adnane, Askew Christopher, Epp Elias, Lavoie Hugo, Whiteway Malcolm, Nantel André
Abstract excerpt
The SAGA/ADA coactivator complex, which regulates numerous cellular processes by coordinating histone acetylation, is widely conserved throughout eukaryotes, and analysis of the Candida albicans genome identifies the components of this complex in the fungal pathogen. We investigated the multiple functions of SAGA/ADA in C. albicans by determining the genome-wide occupancy of Ada2p using chromatin...
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