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Article

Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants

9 Mar 2009

Abstract excerpt

In contrast to the great majority of mycobacterial species that are harmless saprophytes, Mycobacterium tuberculosis and other closely related tubercle bacilli have evolved to be among the most important human and animal pathogens. The need to develop new strategies in the fight against tuberculosis (TB) and related diseases has fuelled research into the evolutionary success of the M. tuberculosis complex...

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PMID: 19274661
DOI: 10.1002/bies.200800191

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