Article
MMPs regulate both development and immunity in the tribolium model insect.
PloS one - 1 Jan 2009
Knorr Eileen, Schmidtberg Henrike, Vilcinskas Andreas, Altincicek Boran
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMPs) are evolutionarily conserved and multifunctional effector molecules in development and homeostasis. In spite of previous, intensive investigation in vitro and in cell culture, their pleiotrophic functions in vivo are still not well understood. METHODOLOGY/PRINCIPAL FINDINGS: We show that the genetically amenable beetle Tribolium castaneum represents a feasible model...
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