Article
Mitochondrial disorders, cognitive impairment and dementia.
Journal of the neurological sciences - 15 Aug 2009
Finsterer Josef
Abstract excerpt
The organ most frequently affected in mitochondrial disorders, particularly respiratory chain diseases (RCDs), in addition to the skeletal muscle, is the central nervous system (CNS). CNS manifestations of RCDs comprise stroke-like episodes, epilepsy, migraine, ataxia, spasticity, movement disorders, psychiatric disorders, cognitive decline, or even dementia (mitochondrial dementia). So far mitochondrial dementia...
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