Article
Neuropathology of mitochondrial diseases.
Bioscience reports - 1 Jun 2007
Filosto Massimiliano, Tomelleri Giuliano, Tonin Paola, Scarpelli Mauro, Vattemi Gaetano, Rizzuto Nicolò, Padovani Alessandro, Simonati Alessandro
Abstract excerpt
The term "mitochondrial diseases" (MD) refers to a group of disorders related to respiratory chain dysfunction. Clinical features are usually extremely heterogeneous because MD may involve several tissues with different degrees of severity. Muscle and brain are mostly affected, probably because of their high dependence on oxidative metabolism. Muscle can be the only affected tissue or involved as a part of a...
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