Article
Expression of MDR1 gene in acute leukemia cells: association with CD7+ acute myeloblastic leukemia/acute lymphoblastic leukemia.
Blood - 1 Dec 1993
Miwa H, Kita K, Nishii K, Morita N, Takakura N, Ohishi K, Mahmud N, Kageyama S, Fukumoto M, Shirakawa S
Abstract excerpt
MDR1 gene expression was examined in acute leukemia cells from 75 Japanese patients at diagnosis (50 with acute myeloblastic leukemia [AML]: 10 M1, 18 M2, 5 M3, 8 M4, 9 M5; 25 with acute lymphoblastic leukemia [ALL]: 13 B-precursor, 12 T-lineage). The results of MDR1 mRNA expression by reverse tr...
Topics
- Adult
- Antigens, CD
- Antigens, CD7
- Antigens, Differentiation, T-Lymphocyte
- Base Sequence
- Drug Resistance
- Gene Expression
- Humans
- Leukemia, Myeloid, Acute
- Molecular Sequence Data
- Phenotype
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- RNA, Messenger