Article
UVA1 is skin deep: molecular and clinical implications.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology - 1 Jan 2013
Tewari Angela, Grage Mette M L, Harrison Graham I, Sarkany Robert, Young Antony R
Abstract excerpt
Long wavelength UVA1 (340-400 nm) is the main component of terrestrial UVR and is increasingly used in skin phototherapy. Its damage to critical biomolecules such as DNA has been widely attributed to its ability to generate reactive oxygen species (ROS) via other chromophores. However recent studies in vitro and in vivo have shown that UVA1 has a specific ability to generate cyclobutane pyrimidine dimers (CPD),...
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