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Article

High dietary intake of sodium selenite does not affect gene mutation frequency in rat colon and liver.

Biological trace element research - 1 Oct 2009

Zeng Huawei, Uthus Eric O, Ross Sharon A, Davis Cindy D

Abstract excerpt

Our previous studies have shown that selenium (Se) is protective against dimethylhydrazine (DMH)-induced preneoplastic colon cancer lesions, and protection against DNA damage has been hypothesized to be one mechanism for the anticancer effect of Se. The present study was designed to determine whether dietary selenite affects somatic mutation frequency in vivo. We used the Big Blue transgenic model to evaluate the...

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PMID: 19263001
DOI: 10.1007/s12011-009-8348-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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