Article
Association of HFE mutations (C282Y and H63D) with iron overload in blood donors from Mexico City.
Annals of hepatology - 1 Jan 2000
Baptista-González Héctor A, Rosenfeld-Mann Fany, Trueba-Gómez Rocío, Bermejo-Martínez Luisa, Méndez-Sánchez Nahum
Abstract excerpt
BACKGROUND AND OBJECTIVE: Iron overload has been associated with HFE mutations (C282Y and H63D). We investigated the association between these mutations and high serum ferritin in a sample of healthy adult men. DESIGN AND METHODS: We enrolled unrelated blood donors from three hospitals in Mexico City in a crosssectional study. Serum ferritin (SF) was determined to define iron overload, and HFE gene mutations were...
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