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Article

Association between the 1793G> A MTHFR polymorphism and sporadic colorectal cancer in Iran.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000

Haghighi Mahdi Montazer, Mohebbi Seyed Reza, Najjar Sadeghi Rouhallah, Vahedi Mohsen, Ghiasi Somayeh, Zali Mohammad Reza

Abstract excerpt

BACKGROUND: It has been proposed that folate and polymorphisms of the enzyme methylenetetrahydrofolate reductase (MTHFR), which regulates influx of folate for methylation reactions for DNA synthesis and repair, are involved in colorectal cancer. This study was designed to determine the influence of a genetic variant (MTHFR G1793A) and folate on colon cancer in Iran. MATERIALS AND METHODS: We analyzed 227 cases...

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Identifiers

PMID: 19256756

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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