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Article

Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk.

Dementia and geriatric cognitive disorders - 1 Jan 2009

Li Keshen, Liu Shengyuan, Yao Songpo, Wang Binyou, Dai Dawei, Yao Lifen

Abstract excerpt

BACKGROUND/AIM: Interleukin-8 (IL-8), a potent chemoattractant for neutrophils, has been implicated in the pathogenesis of Alzheimer's disease (AD). The ability of individuals to produce high levels of IL-8 is partially determined by the IL-8 -251 T/A polymorphism. Therefore, we investigated the association between this polymorphism and AD in a Chinese population. Additionally, in light of the stimulatory effect...

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Source

Identifiers

PMID: 19246914
DOI: 10.1159/000204766

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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