Article
Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension.
Geriatrics & gerontology international - 1 Oct 2010
Oguro Ryosuke, Kamide Kei, Kokubo Yoshihiro, Shimaoka Izumi, Congrains Ada, Horio Takeshi, Hanada Hironori, Ohishi Mitsuru, Katsuya Tomohiro, Okamura Tomonori, Miyata Toshiyuki, Kawano Yuhei, Rakugi Hiromi
Abstract excerpt
AIM: Previous studies suggest that klotho gene polymorphisms may be associated with atherosclerosis, but did not assess the relationship between klotho gene polymorphisms and atherosclerosis parameters such as carotid artery intima-media thickness (IMT). Here, we studied whether klotho single nucleotide polymorphisms (SNP) were associated with carotid atherosclerosis. METHODS: All subjects were Japanese....
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