Article
Competition between NarL-dependent activation and Fis-dependent repression controls expression from the Escherichia coli yeaR and ogt promoters.
The Biochemical journal - 13 May 2009
Squire Derrick J P, Xu Meng, Cole Jeffrey A, Busby Stephen J W, Browning Douglas F
Abstract excerpt
The Escherichia coli NarL protein is a global gene regulatory factor that activates transcription at many target promoters in response to nitrate and nitrite ions. Although most NarL-dependent promoters are also co-dependent on a second transcription factor, FNR protein, two targets, the yeaR and ogt promoters, are activated by NarL alone with no involvement of FNR. Biochemical and genetic studies presented here...
Topics
- Base Sequence
- Binding Sites
- Binding, Competitive
- DNA Footprinting
- DNA-Binding Proteins
- Deoxyribonuclease I
- Electrophoretic Mobility Shift Assay
- Escherichia coli Proteins
- Factor For Inversion Stimulation Protein
- Gene Expression Regulation, Bacterial
- Methyltransferases
- Molecular Sequence Data