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Article

Dependence on nuclear localization signals of the opioid growth factor receptor in the regulation of cell proliferation.

Experimental biology and medicine (Maywood, N.J.) - 1 May 2009

Cheng Fan, McLaughlin Patricia J, Verderame Michael F, Zagon Ian S

Abstract excerpt

The opioid growth factor receptor (OGFr) mediates the inhibitory action of OGF on cell replication of normal and neoplastic cells. The spatiotemporal course of OGFr nucleocytoplasmic trafficking was determined with a probe of full-length OGFr fused to enhanced green fluorescent protein (eGFP). Translation of OGFr required 8.5 hours, and transit into the nucleus required 8 hours; OGFr remained in the nucleus for 8...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19244545
DOI: 10.3181/0901-RM-16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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