Article
A dual role for the adaptor protein DRK in Drosophila olfactory learning and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Feb 2009
Moressis Anastasios, Friedrich Anke R, Pavlopoulos Elias, Davis Ronald L, Skoulakis Efthimios M C
Abstract excerpt
Participation of RAS, RAF, and mitogen-activated protein kinase (MAPK) in learning and memory has been demonstrated in a number of studies, but the molecular events requisite for cascade activation and regulation have not been explored. We demonstrate that the adapter protein DRK (downstream of receptor kinase) which is essential for signaling to RAS in developmental contexts, is preferentially distributed in the...
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