Article
radish encodes a phospholipase-A2 and defines a neural circuit involved in anesthesia-resistant memory.
Current biology : CB - 17 Feb 2004
Chiang Ann-Shyn, Blum Allison, Barditch Jody, Chen Ying-Hsiu, Chiu Shu-Ling, Regulski Michael, Armstrong J Douglas, Tully Tim, Dubnau Josh
Abstract excerpt
BACKGROUND: In both vertebrate and invertebrate animals, anesthetic agents cause retrograde amnesia for recently experienced events. In contrast, older memories are resistant to the same treatments. In Drosophila, anesthesia-resistant memory (ARM) and long-term memory (LTM) are genetically distinct forms of long-lasting memory that exist in parallel for at least a day after training. ARM is disrupted in radish...
Topics
- Alleles
- Amino Acid Sequence
- Anesthesia
- Animals
- Animals, Genetically Modified
- Blotting, Northern
- Blotting, Western
- Brain
- Cold Temperature
- Crosses, Genetic
- DNA Primers
- Drosophila melanogaster
- Enhancer Elements, Genetic