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Article

The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters.

Journal of virology - 1 May 2009

Ottinger Matthias, Pliquet Daniel, Christalla Thomas, Frank Ronald, Stewart James P, Schulz Thomas F

Abstract excerpt

Infection of mice with murine gammaherpesvirus 68 (MHV-68) provides a valuable animal model for gamma-2 herpesvirus (rhadinovirus) infection and pathogenesis. The MHV-68 orf73 protein has been shown to be required for the establishment of viral latency in vivo. This study describes a novel transcriptional activation function of the MHV-68 orf73 protein and identifies the cellular bromodomain containing BET...

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Source

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Identifiers

PMID: 19244327
DOI: 10.1128/JVI.02274-08
PMCID: PMC2668493

Genes

BRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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