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Article

A genetic polymorphism of CYP2C19 is associated with susceptibility to biliary tract cancer.

Journal of gastroenterology - 1 Oct 2010

Isomura Yoshihiro, Yamaji Yutaka, Ohta Miki, Seto Motoko, Asaoka Yoshinari, Tanaka Yasuo, Sasaki Takashi, Nakai Yousuke, Sasahira Naoki, Isayama Hiroyuki, Tada Minoru, Yoshida Haruhiko, Kawabe Takao, Omata Masao, Koike Kazuhiko

Abstract excerpt

PURPOSE: Cytochrome P450 2C19 (CYP2C19) is clinically important for the metabolism of many therapeutic drugs. CYP2C19 has two main point mutation sites leading to low metabolic capacity. Several CYP enzymes are also important for the metabolism of chemical carcinogens, and several studies have re...

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Source

Identifiers

PMID: 20549256
DOI: 10.1007/s00535-010-0246-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20549256-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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