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Article

Role for notch signaling in salivary acinar cell growth and differentiation

22 Feb 2009

Abstract excerpt

The Notch pathway is crucial for stem/progenitor cell maintenance, growth and differentiation in a variety of tissues. The Notch signaling is essential for Drosophila salivary gland development but its role in mammalian salivary gland remains unclear. The human salivary epithelial cell line, HSG, was studied to determine the role of Notch signaling in salivary epithelial cell differentiation. HSG expressed Notch...

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PMID: 19235730
DOI: 10.1002/dvdy.21875

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