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Article

Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3.

Gene - 1 May 2009

Son Do Ngoc, Li LiHua, Katsuyama Hironobu, Komatsu Nahoko, Saito Masayuki, Tanii Hideji, Saijoh Kiyofumi

Abstract excerpt

Among Tissue kallikrein genes (KLKs), KLK1 is abundantly expressed in human skin. Although its putative promoter is known to have various cis-elements, they have not been functionally tested. In the present study, the regulation mechanism of KLK1 promoter supporting such abundant expression was examined. Luciferase assay targeting the KLK1 promoter (nucleotide -1153/+40 from the major transcriptional start site)...

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Source

Identifiers

PMID: 19232384
DOI: 10.1016/j.gene.2009.02.002

Genes

GATA3
KLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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