Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.

doi:10.1006/geno.2000.6330

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Article

Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease.

Genomics - 15 Oct 2000

Yu H, Anderson P J, Freedman B I, Rich S S, Bowden D W

Abstract excerpt

Kallikreins are serine proteases that catalyze the release of kinins and other vasoactive peptides. Previously, we have studied one tissue-specific (H. Yu et al., 1996, J. Am. Soc. Nephrol. 7: 2559-2564) and one plasma-specific (H. Yu et al., 1998, Hypertension 31: 906-911) human kallikrein gene in end-stage renal disease (ESRD). Short sequence repeat polymorphisms for the human plasma kallikrein gene (KLKB1;...

Topics

Alleles
Americas
Animals
Base Sequence
Black People
Chromosomes, Artificial, Bacterial
Exons
Genetic Linkage
Genetic Variation
Humans
Introns
Kidney Failure, Chronic
Molecular Sequence Data
Prekallikrein
Rats
Black or African American

Source

Open in PubMed

Identifiers

PMID: 11031105
DOI: 10.1006/geno.2000.6330

Genes

KLKB1
KLK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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