Article
Replicative capacity differences of thymidine analog resistance mutations in subtype B and C human immunodeficiency virus type 1.
Journal of virology - 1 May 2009
Armstrong Kimberly L, Lee Tun-Hou, Essex M
Abstract excerpt
In order to understand the impact of zidovudine resistance and thymidine analog mutations (TAMs) on subtype C human immunodeficiency virus type 1, we created mutants in subtype C reverse transcriptase (RT). The subtype B RT was placed in a subtype C backbone to act as a control. Mutants and wild-...
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