Article
Does trans-lesion synthesis explain the UV-radiation resistance of DNA synthesis in C. elegans embryos?
Mutation research - 1 Sept 1991
Hartman P, Reddy J, Svendsen B A
Abstract excerpt
Over 10-fold larger fluences were required to inhibit both DNA synthesis and cell division in wild-type C. elegans embryos as compared with other model systems or C. elegans rad mutants. In addition, unlike in other organisms, the molecular weight of daughter DNA strands was reduced only after large, superlethal fluences. The molecular weight of nascent DNA fragments exceeded the interdimer distance by up to...
Topics
- Animals
- Caenorhabditis
- Cell Division
- DNA
- DNA Damage
- Microscopy, Fluorescence
- Mutation
- Ultraviolet Rays
