Article
Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells.
Biology of the cell - 4 Jun 2009
Nicolier Magali, Decrion-Barthod Anne-Zélie, Launay Sophie, Prétet Jean-Luc, Mougin Christiane
Abstract excerpt
BACKGROUND INFORMATION: Caspase-dependent and -independent death mechanisms are involved in apoptosis in a variety of human carcinoma cells treated with antineoplastic compounds. Our laboratory has reported that p53 is a key contributor of mitochondrial apoptosis in cervical carcinoma cells after...
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