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Article

Cisplatin-resistant HeLa cells are resistant to apoptosis via p53-dependent and -independent pathways.

Japanese journal of cancer research : Gann - 1 Dec 1999

Minagawa Y, Kigawa J, Itamochi H, Kanamori Y, Shimada M, Takahashi M, Terakawa N

Abstract excerpt

Since HeLa cells possess very little functional p53 activity, they could be originally resistant to genotoxic stress-induced apoptosis. Therefore, it is likely that the drug-resistant cells derived from HeLa cells are more resistant to apoptosis. The aim of this study was to determine whether cisplatin-resistant cells derived from HeLa cells have an apoptosis-resistant phenotype. A cisplatin-resistant cell...

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Identifiers

PMID: 10665656
DOI: 10.1111/j.1349-7006.1999.tb00722.x
PMCID: PMC5926032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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