Article
Life without a wall or division machine in Bacillus subtilis.
Nature - 12 Feb 2009
Leaver M, Domínguez-Cuevas P, Coxhead J M, Daniel R A, Errington J
Abstract excerpt
The cell wall is an essential structure for virtually all bacteria, forming a tough outer shell that protects the cell from damage and osmotic lysis. It is the target of our best antibiotics. L-form strains are wall-deficient derivatives of common bacteria that have been studied for decades. However, they are difficult to generate and typically require growth for many generations on osmotically protective media...
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