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Article

L-form bacteria, chronic diseases and the origins of life.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Nov 2016

Errington Jeff, Mickiewicz Katarzyna, Kawai Yoshikazu, Wu Ling Juan

Abstract excerpt

The peptidoglycan cell wall is widely conserved across the bacterial domain, suggesting that it appeared early in the evolution of bacteria. It is normally essential but under certain conditions wall-deficient or 'L-form' bacteria can be isolated. In Bacillus subtilis this normally requires two genetic changes. The first, exemplified by mutations shutting down wall precursor synthesis, works by increasing...

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Identifiers

PMID: 27672147
DOI: 10.1098/rstb.2015.0494
PMCID: PMC5052740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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