Article
Excess membrane synthesis drives a primitive mode of cell proliferation.
Cell - 28 Feb 2013
Mercier Romain, Kawai Yoshikazu, Errington Jeff
Abstract excerpt
The peptidoglycan cell wall is a hallmark of the bacterial subkingdom. Surprisingly, many modern bacteria retain the ability to switch into a wall-free state called the L-form. L-form proliferation is remarkable in being independent of the normally essential FtsZ-based division machinery and in occurring by membrane blebbing and tubulation. We show that mutations leading to excess membrane synthesis are...
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