Article
A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in a Bangladeshi population.
Genes and immunity - 1 Apr 2009
Larocque R C, Sabeti P, Duggal P, Chowdhury F, Khan A I, Lebrun L M, Harris J B, Ryan E T, Qadri F, Calderwood S B
Abstract excerpt
Vibrio cholerae causes a dehydrating diarrheal illness that can be rapidly fatal in the absence of specific treatment. The organism is an historic scourge and, like similar infectious diseases, may have influenced the evolution of the human genome. We report here the results of the first candidate gene association study of cholera. In a family-based study of 76 pedigrees from Dhaka, Bangladesh, we evaluated the...
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