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Article

Genomic Profiles Associated with Early Micrometastasis in Lung Cancer: Relevance of 4q Deletion

10 Feb 2009

Abstract excerpt

PURPOSE: Bone marrow is a common homing organ for early disseminated tumor cells (DTC) and their presence can predict the subsequent occurrence of overt metastasis and survival in lung cancer. It is still unclear whether the shedding of DTC from the primary tumor is a random process or a selective release driven by a specific genomic pattern. EXPERIMENTAL DESIGN: DTCs were identified in bone marrow from lung...

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PMID: 19208797
DOI: 10.1158/1078-0432.ccr-08-2188

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