Article
Review article: Luminex technology for HLA antibody detection in organ transplantation.
Nephrology (Carlton, Vic.) - 1 Apr 2009
Tait Brian D, Hudson Fiona, Cantwell Linda, Brewin Gemma, Holdsworth Rhonda, Bennett Greg, Jose Matthew
Abstract excerpt
Since its inception in the early 1960s, the serologically based complement-dependent cytotoxicity (CDC) assay has been the cornerstone technique for the detection of human leucocyte antigen (HLA) antibodies, not only in pre-transplant renal patients, but also in other forms of organ transplantation. Recently, solid phase assays have been developed and introduced for this purpose, and in particular the Flow-based...
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