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Article

Oncogenic role of nuclear accumulated Aurora-A.

Molecular carcinogenesis - 1 Sept 2009

Tatsuka Masaaki, Sato Sunao, Kanda Akifumi, Miki Tomoharu, Kamata Nobuyuki, Kitajima Shojiro, Kudo Yasusei, Takata Takashi

Abstract excerpt

Aurora-A, also known as Aik, BTAK, or STK15, is a centrosomal serine/threonine protein kinase, which is proto-oncogenic and is overexpressed in a wide range of human cancers. Besides gene amplification and mRNA overexpression, proteolytic resistance mechanisms are thought to contribute to overexp...

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PMID: 19204928
DOI: 10.1002/mc.20525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19204928-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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