Article
Genetic association studies in ischaemic stroke: replication failure and prospects.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2009
Pruissen D Martijn O, Kappelle L Jaap, Rosendaal Frits R, Algra Ale
Abstract excerpt
Although hundreds of genetic association studies of ischaemic stroke have been published, the failure to replicate associations has led to scepticism about their findings. Possible explanations for this failure are: (1) a false-positive association in the initial study; (2) a false-negative assoc...
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