rs660 polymorphism in Ro52 (SSA1; TRIM21) is a marker for age-dependent tolerance induction and efficiency of alloimmunization in sickle cell disease.

doi:10.1016/j.molimm.2008.12.027

Article

rs660 polymorphism in Ro52 (SSA1; TRIM21) is a marker for age-dependent tolerance induction and efficiency of alloimmunization in sickle cell disease.

Molecular immunology - 1 Nov 2009

Tatari-Calderone Zohreh, Minniti Caterina P, Kratovil Tonya, Stojakovic Milica, Vollmer Alison, Barjaktarevic Igor, Zhang Ed, Hoang Albert, Luban Naomi L C, Vukmanovic Stanislav

Abstract excerpt

Patients with sickle cell disease (SCD) who receive red blood cell (RBC) transfusions have a higher rate of anti-RBC (allo and auto) antibody development than other transfused subjects. We hypothesized that an incidence and/or kinetics of RBC-specific antibody formation in SCD patients is influen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

rs660 polymorphism in Ro52 (SSA1; TRIM21) is a marker for age-dependent tolerance induction and efficiency of alloimmunization in sickle cell disease.

Abstract excerpt

Topics

Related research