Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.

doi:10.1002/ajmg.b.30932

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Article

Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2009

Terracciano Antonio, Balaci Lenuta, Thayer Jason, Scally Matthew, Kokinos Sarah, Ferrucci Luigi, Tanaka Toshiko, Zonderman Alan B, Sanna Serena, Olla Nazario, Zuncheddu Maria Antonietta, Naitza Silvia, Busonero Fabio, Uda Manuela, Schlessinger David, Abecasis Gonçalo R, Costa Paul T

Abstract excerpt

The polymorphism in the serotonin transporter gene promoter region (5-HTTLPR) is by far the most studied variant hypothesized to influence Neuroticism-related personality traits. The results of previous studies have been mixed and appear moderated by the personality questionnaire used. Studies that used the TCI to assess Harm Avoidance or the EPQ to assess Neuroticism have found no association with the 5-HTTLPR....

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PMID: 19199283
DOI: 10.1002/ajmg.b.30932
PMCID: PMC2788669

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