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Article

Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism.

Molecular psychiatry - 1 Jan 1999

Flory J D, Manuck S B, Ferrell R E, Dent K M, Peters D G, Muldoon M F

Abstract excerpt

A deletion/insertion polymorphism in the transcriptional control region of the serotonin transporter gene (5-HTTLPR) was reported to be associated with dimensional measures of neuroticism, although subsequent replication attempts have failed. These replication attempts, however, have been dissimilar to the initial study in sample size, distribution of allelic frequency and/or assessment of neuroticism. The...

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PMID: 10089017
DOI: 10.1038/sj.mp.4000466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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