Article

Molecular Genetics of Thyroid Dysgenesis: Established and Emerging Contributors

2025-10-27

Abstract excerpt

Congenital hypothyroidism (CH) is one of the most common endocrine disorders of childhood. The primary form of CH is attributable to thyroid dysgenesis (agenesis, hypoplasia, or ectopy) in 65-85% of cases, with the remaining cases being attributed to dyshormogenesis. Thyroid dysgenesis was considered a sporadic disease. However, the recent advantages of molecular techniques have significantly contributed to the un...

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Literature Corpus work: ff5e68c0-8223-5889-99a4-39138d609917
DOI: 10.20944/preprints202510.1921.v1

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