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Live Birth of Somatic Cell-Cloned Rabbits following Trichostatin A Treatment and Cotransfer of Parthenogenetic Embryos

28 Jan 2009

Abstract excerpt

Somatic cell nuclear transfer (SCNT) efficiency is still low in rabbit. Previous studies indicated that trichostatin A (TSA) treatment could improve cloning efficiency and term development in the mouse, and cotransfer of parthenogenetic (PA) embryos benefited the pregnancy of cloned embryos in porcine and the mouse. In this study we investigated the effect of TSA treatment on the term development of the SCNT...

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PMID: 19196041
DOI: 10.1089/clo.2008.0072

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Live Birth of Somatic Cell-Cloned Rabbits following Trichostatin A Treatment and Cotransfer of Parthenogenetic EmbryosPMID 19196041Read ↗

Trichostatin A (TSA) improves the development of rabbit‐rabbit intraspecies cloned embryos, but not rabbit‐human interspecies cloned embryosSemantic proximity Read ↗

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Acetylation Level of Histone H3 in Early Embryonic Stages Affects Subsequent Development of Miniature Pig Somatic Cell Nuclear Transfer EmbryosSemantic proximity Read ↗

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Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transferSemantic proximity Read ↗

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