[Tenofovir DF in rescue regimens].

Abstract excerpt

As with other nucleoside analogues, tenofovir (TDF) can be affected by several mutations in the reverse transcriptase gene. Most nucleoside analogue mutations (NAMs) are not induced specifically by TDF, although they can affect the activity of this drug. The impact of thymidine analogue mutations (TAMs) on tenofovir varies and, as with the remaining nucleoside analogue reverse transcriptase inhibitors, largely...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Thymidine
• Share to Zalcitabine
• Share to Antimetabolites