Article
Patterns of resistance emerging in HIV-1 from antiretroviral-experienced patients undergoing intensification therapy with tenofovir disoproxil fumarate.
Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2004
McColl Damian J, Margot Nicolas A, Wulfsohn Michael, Coakley Dion F, Cheng Andrew K, Miller Michael D
Abstract excerpt
Study GS-99-907 was a 48-week, phase 3, double-blind, placebo-controlled intensification trial of tenofovir disoproxil fumarate (tenofovir DF). Antiretroviral-experienced patients added tenofovir DF 300 mg once daily to their existing regimen. The patterns of HIV-1 resistance development and the corresponding virologic responses were evaluated in a virology substudy at week 48. Although 94% of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
