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Article

Genetic association between CALHM1, 2, and 3 polymorphisms and Alzheimer's disease in a Japanese population.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Shibata Nobuto, Kuerban Bolati, Komatsu Miwa, Ohnuma Tohru, Baba Hajime, Arai Heii

Abstract excerpt

A recent paper reported that a variant (rs2986017) of the calcium homeostasis modulator 1 (CALHM1) gene affects risk for late-onset Alzheimer's disease (AD). This study aims to investigate whether single nucleotide polymorphisms (SNPs) of the CALHM1 gene are associated with AD. SNPs in the genes of two other CALHM subtypes, CALHM2 and CALHM3, were also studied. Our study failed to detect any association between...

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Alzheimer Disease
Apolipoprotein E4
Calcium Channels
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Membrane Glycoproteins

Regression Analysis

Source

Identifiers

PMID: 20164573
DOI: 10.3233/JAD-2010-1380

Genes

CALHM1
CALHM2
CALHM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Genetic association between CALHM1, 2, and 3 polymorphisms and Alzheimer's disease in a Japanese population.PMID 20164573Read ↗

Genetic association of CALHM1 rs2986017 polymorphism with risk of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Lack of association between CALHM1 p.P86L variation and Alzheimer's disease in the Han Chinese population.Semantic proximity Read ↗

No association between CALHM1 variation and risk of Alzheimer disease.Semantic proximity Read ↗

No association between CALHM1 polymorphism and Alzheimer's disease risk in a Hungarian population.Semantic proximity Read ↗

Calcium homeostasis modulator 1 gene P86L polymorphism and the risk for alzheimer's disease: A meta-analysis.Semantic proximity Read ↗

A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.Semantic proximity Read ↗

CALHM1 variant is not associated with Alzheimer's disease among Asians.Semantic proximity Read ↗

No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.Semantic proximity Read ↗

CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease.Semantic proximity Read ↗

Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.Semantic proximity Read ↗

The P86L common allele of CALHM1 does not influence risk for Alzheimer disease in Japanese cohorts.Semantic proximity Read ↗

The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study.Semantic proximity Read ↗

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