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Article

Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni.

PLoS neglected tropical diseases - 1 Jan 2009

Gatlin Michael R, Black Carla L, Mwinzi Pauline N, Secor W Evan, Karanja Diana M, Colley Daniel G

Abstract excerpt

BACKGROUND: The immunologic findings that most consistently correlate with resistance in human schistosomiasis are high levels of IgE and low levels of IgG4. We have genotyped gene and promoter polymorphisms of cytokines associated with regulation of these isotypes in a cohort of men occupationally exposed to Schistosoma mansoni in western Kenya and evaluated their patterns with respect to resistance and...

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Identifiers

PMID: 19190772
DOI: 10.1371/journal.pntd.0000375
PMCID: PMC2631135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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