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Article

Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis.

The Journal of clinical endocrinology and metabolism - 1 Apr 2009

Subramanian Mahesh, Pilli Tania, Bhattacharya Palash, Pacini Furio, Nikiforov Yuri E, Kanteti Prasad V, Prabhakar Bellur S

Abstract excerpt

AIM: The aim of the study was to investigate the expression and function of the IG20 gene in thyroid cancer cell survival, proliferation, and apoptosis. METHODS: We determined the expression levels of the major isoforms of IG20 by quantitative RT-PCR in normal and thyroid tumor tissues/cell lines. We evaluated the functional consequence of IG20 knockdown in WRO (follicular carcinoma) and FRO (anaplastic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA, Neoplasm

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Source

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Identifiers

PMID: 19190106
DOI: 10.1210/jc.2008-2378
PMCID: PMC2682475

Genes

MADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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