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Article

IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs.

Oncogene - 5 Feb 2004

Efimova Elena V, Al-Zoubi Adeeb M, Martinez Osvaldo, Kaithamana Shashi, Lu Shenfeng, Arima Takayasu, Prabhakar Bellur S

Abstract excerpt

We identified seven putative splice variants of the human IG20 gene. Four variants namely, IG20, MADD, IG20-SV2 and DENN-SV are expressed in human tissues. While DENN-SV is constitutively expressed in all tissues, expression of IG20 appears to be regulated. Interestingly, overexpression of DENN-S...

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Source

Identifiers

PMID: 14716293
DOI: 10.1038/sj.onc.1207210

Genes

MADD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14716293-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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