Article
Increase in presynaptic territory of C-terminals on lumbar motoneurons of G93A SOD1 mice during disease progression.
The European journal of neuroscience - 1 Feb 2009
Pullen A H, Athanasiou D
Abstract excerpt
Compensatory synaptic plasticity is reported in muscle and the central nervous system of motor neuron disease patients, and transgenic SOD1 mice, but direct ultrastructural evidence for spinal motoneurons is lacking. Prompted by our observation in spinal cords from autopsied patients suggesting selective enlargement of the ultrastructurally distinctive C-type terminal synapsing with spinal motoneurons, we...
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