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[Molecular mechanisms of Glanzmann thrombasthenia caused by alpha II b L721R and Q860X compound heterozygous mutation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Sept 2008

Shen Wei-Zhang, Jin Pei-Pei, Ding Qiu-Lan, Wang Xue-Feng, Li Shu-Mei, Jiang Yu-Zhen, Wang Hong-Li

Abstract excerpt

OBJECTIVE: To explore the molecular mechanisms of Glanzmann thrombasthenia caused by alpha II b L721R and Q860X compound heterozygous mutation. METHODS: All exons and exon-intron boundaries of alpha II b and beta3 gene were amplified by PCR and analyzed by direct DNA sequencing. Gene polymorphisms were excluded by direct DNA sequencing. Alpha II b L721R and Q860X mutants expressing vectors were constructed by in...

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PMID: 19175981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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