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[Analysis of molecular pathogenesis and clinical phenotypes in 10 probands with inherited fibrinogen deficiency].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2015

Zhu Liqing, Zhao Misheng, Lin Jie, Wang Yingyu, Xie Haixiao, Xie Yaosheng, Ding Hongxiang, Wang Mingshan

Abstract excerpt

OBJECTIVE: To explore the molecular pathogenesis and clinical phenotypes in 10 probands with inherited fibrinogen (Fg) deficiency. METHODS: The diagnosis of hereditary Fg deficiency was validated by prothrombin time (PT), thrombin time (TT), Fg activity (Fg:C) and Fg antigen (Fg:Ag) in plasma. All of the exons and their flanking sequences of the Fg gene were analyzed by direct sequencing. Detected mutations were...

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Identifiers

PMID: 26663050
DOI: 10.3760/cma.j.issn.1003-9406.2015.06.008

Genes

FGG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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